BioMarin也迅速跟进迭代研发,其升级版在研产品BMN333同样旨在实现周剂注射。早期临床结果显示BMN333的AUC水平高于其他长效CNP研究的3倍以上,公司研发主管Greg Friberg表示该药对标的正是TransCon-CNP。
Donald Trump has spent much of his second term at war with science and scientists. He is cutting staff at institutions such as the Environmental Protection Agency (EPA) by a third, and has cancelled or frozen up to 8,000 federal research grants. This hasn’t just hurt individual research programmes, it has damaged America’s credibility as a reliable partner in the scientific community. It is not surprising that many researchers – one poll last year by the journal Nature gave the number of 75% – say they are considering leaving the US entirely.
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